Autolus Therapeutics to Present New Data at the Virtual 2020 AACR Annual Meeting
- Preclinical data on AUTO5 in T cell lymphoma and solid tumor data on AUTO6NG in small cell lung cancer and AUTO7 in prostate cancer -
Conference Call and Webcast to be held Thursday, June 25, 2020 at
Oral Presentation Title: AUTO7: Anti-PSMA humanized CAR T cell with improved persistence and resistance to tumor microenvironment for metastatic castration resistant prostate cancer (mCRPC)
Session Title: Mini-symposium; MS.IM02.01 - Adoptive Cell Therapy
Abstract: 1070
Date & Time: June 23, 2020,
Presenter: Dr
Poster Presentation Title: AUTO6NG overcomes immune suppressive mechanisms in the TME and demonstrate preclinical anti-tumor activity in GD2-expressing solid tumors
Poster Session Title: Poster Session; PO.TB06.05 - Immune Cells in the Tumor Microenvironment 2
Poster: 2661 / 9
Date & Time: June 22, 2020,
Presenter: Dr
Poster Presentation Title: Targeting TRBC1 and 2 for the treatment of T cell lymphomas
Poster Session Title: Poster Session; PO.IM02.02 - Adoptive Cell Therapy 2
Poster: 2183 / 15
Date & Time: June 22, 2020,
Presenter: Dr
Investor call on Thursday June 25, 2020
Management will host a conference call and webcast at 8:30 am EDT/
The call may also be accessed by dialing (866) 679-5407 for
About
About AUTO5
AUTO5 is a programmed T cell product candidate in pre-clinical development for T cell lymphoma, a setting where there are currently no approved programmed T cell therapies. AUTO5 is specifically designed to target TRBC2 derived cancers, which account for approximately 60% of T cell lymphomas, and is a complement to the AUTO4 T cell product candidate currently in clinical development.
About AUTO6NG
AUTO6NG is a next generation programmed T cell product candidate in pre-clinical development. AUTO6NG builds on preliminary proof of concept data from AUTO6, a CAR targeting GD2-expression cancer cell currently in clinical development for the treatment of Neuroblastoma. AUTO6NG incorporates additional cell programming modules to overcome immune suppressive defense mechanisms in the tumor microenvironment, in addition to endowing the CAR-T cells with extended persistence capacity. AUTO6NG is currently in preclinical development for the potential treatment of other GD2-expressing solid tumors than Neuroblastoma, including Osteosarcoma, Soft Tissue Sarcoma, Small Cell
About AUTO7
AUTO7 is a next generation programmed T cell product candidate in pre-clinical development for the treatment of advanced prostate cancer. It encodes a CAR harboring a highly sensitive and stable binder to the prostate ligand PSMA. In addition, AUTO7 incorporates four novel cell programming modules: a truncated
Contact:
Vice President, Investor Relations and Corporate Communications
+44 (0) 7587 372 619
l.crabtree@autolus.com
+44 (0) 7818 430877
j.wilson@autolus.com
+1-212-966-3650
susan@sanoonan.com
Source: Autolus Therapeutics plc