0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Condensed Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Condensed Consolidated Statements of Operations and Comprehensive Loss (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Condensed Consolidated Statements of Changes in Shareholders’ Equity link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - Condensed Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952157 - Disclosure - Nature of the Business link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Revenue link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Interest Expense, Net link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Net Loss Per Share link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Marketable Securities: Available-For-Sale Debt Securities link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Inventories, Net link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Prepaid Expenses and Other Current Assets link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Property and Equipment, Net link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Intangible Assets, Net link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Accrued Expenses and Other Liabilities link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Shareholders’ Equity link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Share-Based Compensation link:presentationLink link:calculationLink link:definitionLink 9952171 - Disclosure - Liabilities Related to Future Royalties and Milestones, Net link:presentationLink link:calculationLink link:definitionLink 9952172 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 9952173 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952174 - Disclosure - Segment Reporting link:presentationLink link:calculationLink link:definitionLink 9952175 - Disclosure - Related Party Transactions link:presentationLink link:calculationLink link:definitionLink 9952176 - Disclosure - Subsequent Events link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Revenue (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Interest Expense, Net (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Net Loss Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Marketable Securities: Available-For-Sale Debt Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Inventories, Net (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Prepaid Expenses and Other Current Assets (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Property and Equipment, Net (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Intangible Assets, Net (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Accrued Expenses and Other Liabilities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Share-Based Compensation (Tables) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Liabilities Related to Future Royalties and Milestones, Net (Tables) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Segment Reporting (Tables) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Summary of Significant Accounting Policies (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Revenue - Schedule of Product Revenue, Net by Geographical Location (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Revenue - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Revenue - Schedule of Current Accruals for Rebates and Chargebacks (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Interest Expense, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Net Loss Per Share - Schedule of Basic and Diluted Net Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Net Loss Per Share - Schedule of Potentially Dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Fair Value Measurements (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Marketable Securities: Available-For-Sale Debt Securities - Schedule of Investments in Available-for-Sale Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Marketable Securities: Available-For-Sale Debt Securities - Schedule of Securities in an Unrealized Loss Position (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Marketable Securities: Available-For-Sale Debt Securities - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Inventories, Net - Schedule of Inventories, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Inventories, Net - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Prepaid Expenses and Other Current Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Property and Equipment, Net - Schedule of Property and Equipment, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Property and Equipment, Net - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Intangible Assets, Net - Schedule of Carrying Amount of Intangible Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Intangible Assets, Net - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Accrued Expenses and Other Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Shareholders’ Equity (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Share-Based Compensation - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Share-Based Compensation - Schedule of Total Share-based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Share-Based Compensation - Schedule of Share Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Share-Based Compensation - Schedule of RSU Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Liabilities Related to Future Royalties and Milestones, Net - Schedule of Carrying Value (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - Disclosure - Liabilities Related to Future Royalties and Milestones, Net - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Leases - Schedule of Lease Cost (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Leases - Schedule of Supplemental Cash Flow Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955554 - Disclosure - Leases - Schedule of Weighted Average Remaining Lease Term and Weighted Average Discount Rate of Operating Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955555 - Disclosure - Leases - Schedule of Maturities of Operating Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955555 - Disclosure - Leases - Schedule of Maturities of Operating Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955556 - Disclosure - Commitments and Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 9955557 - Disclosure - Segment Reporting - Schedule of Segment Loss, Including Significant Segment Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955558 - Disclosure - Related Party Transactions (Details) link:presentationLink link:calculationLink link:definitionLink 9955559 - Disclosure - Subsequent Events (Details) link:presentationLink link:calculationLink link:definitionLink